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Saturday, 13 June 2015

Job Responsibility: Quality Assurance Lead

JOB RESPONSIBILITY


Name:                                                          Department: Quality Assurance
Designation: Quality Assurance Lead                          Area/Lab/Section: Quality Assurance

1.   General Instructions:

1.1.      Each individual shall undertake the said duties but has to work alongwith the team in order to assume collective responsibilities. Individual adventurism of any sort is not encouraged.
1.2.      Any deviation observed during discharge of official duties is to be reported to the superiors immediately.
1.3.      Any person working in shifts has the additional responsibility of briefing the personnel working in the next shift about the work done and that to be undertaken subsequently.
1.4.      Addition or deprivation of duties and responsibilities shall depend on the performance of the individual.

2.    Duties/Responsibilities:

2.1.      QA In charge shall ensure Quality Management System shall be established, documented, implemented and maintained and continually improve for its effectiveness in accordance to require standards.
2.2.      Shall identify the statutory and regulatory requirements applicable to all the products manufactured in the plant and shall ensure that these requirements are met.
2.3.      Shall identify all the processes falling under company’s QMS and identify their sequence of interactions. Shall also ensure that all the processes meet latest GXP requirements.
2.4.      Shall review and submit all the documents and dossiers required by the state, zonal, national and international regulatory departments.
2.5.      Shall ensure that there is proper organization of documentation system and all the documents are segregated and prepared as per the hierarchy document system (level 1, 2, 3 and 4 documents).
2.6.      Ensure that the documents are periodically reviewed and updated.
2.7.      Shall establish and maintain quality manual, define quality policy and establish quality objectives.
2.8.      Shall ensure that Level 2 documents (policies and plans) are established as per the latest requirements and ensure their implementation at all the levels of Quality System.
2.9.      Shall ensure that level 3 (Standard operating procedures) and level 4 (records, test methods, specifications, validations) are prepared and implemented in all the departments of the quality management system.
2.10.   Shall ensure that effectiveness of QMS is continually improved through the use of the quality policy, quality objectives, audit results, analysis of data, corrective and preventive actions and management review.
2.11.   Shall ensure that the integrity of the quality management system is maintained when changes to the quality management system or its components are planned and implemented.
2.12.   Shall ensure that the procedure for root cause analysis, corrective action and preventive action are in place and are effectively implemented.
2.13.   Shall review and authorize all the documents and records pertaining to the quality of the product and QMS.
2.14.   Shall review and authorize summary protocols of all the production batches.
2.15.   Shall authorize release of intermediate, drug substance and drug product.
2.16.   Shall authorize manufacture of the batch as per the production plan and ensure that manufacturing is done as per the set procedures and specifications so that the product meets its desired specifications.
2.17.   Shall facilitate internal, external and regulatory audits and inspection and shall all the audit points and suggestions are complied within the stipulated time period.
2.18.   Shall ensure that all the market complaints are investigated and resolved as per the national regulatory guidelines and facilitate product recall if any as per the set guidelines.
2.19.   Shall ensure that suitable methods for monitoring and, where applicable, measurement of the quality management system processes are in place.
2.20.   Shall ensure that the characteristics of the product are monitor and measure to verify that product requirements have been met.
2.21.   Shall ensure that product which does not conform to product requirements is identified and controlled to prevent its unintended use or delivery.
2.22.   Shall ensure that top management shall review the organization's quality management system, at planned intervals, to ensure its continuing suitability, adequacy and effectiveness.
2.23.   Shall ensure that all the staff involved in manufacturing, control and testing and support functions are competent on the basis of appropriate education, training, skills and experience. The staff shall be trained in the aspects of job function, hygiene, GXP and other areas deemed necessary.
2.24.   Shall ensure that all the quality assurance functions are planned and executed accordingly.
2.25.   Shall ensure that the procedure of vendor approval is in place and all the material and services taken by the organization shall follow this approval process. List of approved vendors shall be prepared.
2.26.   Shall ensure that proper control is there on all the outsourced activities and shall be within the umbrella of quality management system.
2.27.   Assign job responsibilities to Quality Assurance staff.
2.28.   Undertake other duties as determined by superiors.

3.    Authorities:

3.1.      Authorize initiation of production batch.
3.2.      Authorize final release, distribution and recall of various products of the company in the market.
3.3.      Authorize distribution and control of various audits documents for Registration, License and Tendering purpose.
3.4.      Authorize investigation for process / product complaints for non-conformity.
3.5.      Approval of various Quality related policies of the company.
3.6.      Authorize all the documents prepared as per the hierarchy document system (level 1, 2, 3 and 4 documents).

4.    Reporting:

4.1.      Report to plant head/ factory manager all the daily activities and plans.

Assigned By CMD                                                                                       
(Signature and Date)
         
                                                                                              
Jobholder

(Signature and Date)

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